Invitrogen™ eIF5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA565258

Product Code. 15978014

Description

Immunogen sequence: EGKLLTKSQRE ARARAEATLK LLQAQGVEVP SKDSLPKKRP IYEDKKRKKI PQQLESKEVS ESMELCAAVE VMEQGVPEKE Highest antigen sequence identity to the following orthologs - mouse 81%, rat 81%.

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.

Specifications

• Antigen: eIF5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF5B
• Gene Alias: A030003E17Rik; Annexin V-binding protein ABP-7; BC018347; DKFZp434I036; eIF 5B; Eif5b; eIF-5B; Eukaryotic translation initiation factor 5B; FLJ10524; If2; KIAA0741; translation initiation factor IF2; Translation initiation factor IF-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9669
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60841
• Gene Symbols: EIF5B
• Immunogen: Recombinant Human eIF5B. Recombinant protein control fragment (Product #RP-104713).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG