eIF5B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA539166

Product Code. 15506081

Description

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.

Specifications

• Antigen: EIF5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF5B
• Gene Alias: Eukaryotic translation initiation factor 5B, Translation initiation factor IF2, IF2, FLJ10524, KIAA0741, DKFZp434I036, Translation initiation factor IF 2, eIF 5B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 226982, 308306, 9669
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O60841, Q05D44, B2GUV7
• Gene Symbols: EIF5B
• Immunogen: A synthetic peptide derived from the internal region of human EIF5B
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG