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eIF4E Monoclonal Antibody (5D11), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA1089

Code : PN

Additional Details : Weight : 0.01000kg

Product Code. 13441007

  • £419.00 / 100µg
Estimated Shipment: 12-08-2024
to see stock.

Description

Description

MA1-089 detects eIF4E in human and mouse samples and has been successfully used in Western blot, immunofluorescence, immunocytochemistry and immunoprecipitation applications. MA1-089 does not react with rat eIF4E. The MA1-089 immunogen is full length human eIF4E produced in HEK293T cells.

eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.
Specifications

Specifications

eIF4E
Monoclonal
1 mg/mL
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
P06730, P63073
Eif4e
Full length human eIF4E produced in HEK293T cells
100 μg
Primary
Human, Mouse
Antibody
IgG1
Immunocytochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot
5D11
Unconjugated
Eif4e
AUTS19; CBP; EG668879; EIF4E; EIF-4E; EIF4E1; EIF4EL1; Eif4e-ps; EIF4F; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; eukaryotic translation initiation factor 4E-like protein; eukaryotic translation initiation factor 4-like protein; If4e; MGC111573; mRNA cap-binding protein; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; translation initiation factor eIF-4E
Mouse
Protein A
RUO
13684, 1977
-20°C
Liquid
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