EIF3D Rabbit anti-Human, Mouse, Yeast, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10219-1-AP-20UL

Product Code. 16856463

Description

eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.

Specifications

• Antigen: EIF3D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF3D
• Gene Alias: eIF 3 zeta, eIF3 p66, eIF3 zeta, EIF3D, EIF3S7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55944, 8664
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Concentration: 0.29 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: O15371, O70194
• Gene Symbols: Eif3d
• Immunogen: EIF3D Fusion Protein Ag0268
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Yeast, Human
• Product Type: Antibody
• Isotype: IgG