Invitrogen™ eIF2b alpha Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5121151

Product Code. 17792544

Description

Positive test controls include: SH-SY5Y, MCF7, SKOV3, NCI-H460, Mouse liver, Mouse brain. Immunogen sequence: MDDKELIEYF KSQMKEDPDM ASAVAAIRTL LEFLKRDKGE TIQGLRANLT SAIETLCGVD SSVAVSSGGE LFLRFISLAS LEYSDYSKCK KIMIERGELF LRRISLSRNK IADLCHTFIK DGATILTHAY SRVVLRVLEA AVAAKKRFSV YVTESQPDLS GKKMAKALCH LNVPVTVVLD AAVGYIMEKA DLVIVGAEGV VENGGIINKI GTNQMAVCAK AQNKPFYVVA ESFKFVRLFP LNQQDVPDKF KYKADTLKVA QTGQDLKEEH PWVDYTAPSL ITLLFTDLGV LTPSAVSDEL IKLYL.

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Specifications

• Antigen: eIF2b alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF2B1
• Gene Alias: 26kDa; D5Ertd406e; eIF-2a; EIF2B; eIF-2B GDP-GTP exchange factor subunit alpha; Eif2b1; EIF2BA; eIF-2Balpha; eukaryotic translation initiation factor 2B subunit alpha; eukaryotic translation initiation factor 2B, subunit 1 (alpha); eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa); eukaryotic translation initiation factor 2B, subunit 1 alpha; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; GTP-exchange protein; translation initiation factor eIF-2B subunit alpha
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1967, 209354
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q14232, Q99LC8
• Gene Symbols: EIF2B1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human EIF2B1 (NP_001405.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG