Human EIF2AK2 (PKR), GST Tag Recombinant Protein

Human EIF2AK2 (PKR), GST Tag Recombinant Protein

Brand:  Invitrogen PV4821

Product Code. 10022913

Description

EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.

Specifications

• Accession Number: NP_002750.1
• Gene ID (Entrez): 9833
• Quantity: 10 μg
• KinaseFamily: PEK Kinase Family
• Species: Human
• Protein Tag: GST Tag
• Assay Entry: Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
• Shipping Condition: Dry Ice
• Target Entry: EIF2AK2
• Expression System: Baculovirus
• Protein Form: Recombinant, Catalytic
• Protein Subtype: Serine/Threonine Kinases

• For Use With (Application): Kinase Assay
• Molecular Weight (g/mol): 62.2 kDa
• Gene Alias: EIF2AK2 (PKR)
• Protein Length: aa 252-551
• Recombinant: Recombinant
• Content And Storage: Storage Buffer: 50 mM Tris, pH 7.5, 50% glycerol, 0.5 mM EDTA, 0.02% Triton X-100, 150 mM NaCl, 2 mM DTT
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Kinase Group: Ser⁄Thr Kinases: Other
• System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate
• Target Gene: eukaryotic translation initiation factor 2-alpha kinase 2
• Protein Family: Kinases & Inhibitors
• Form: Liquid
• Research Category: Signal Transduction