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Invitrogen™ Human EIF2AK1 (HRI), GST Tag Recombinant Protein

Product Code. 15488793
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Quantity:
1 mg
100 μg
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100µg
1mg
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Product Code. 15488793

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK1, signaling is initiated by low levels of heme. The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands and kinase activity is induced by low levels of heme and inhibited by the presence of heme.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9BQI3
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris with no preservative
Gene ID (Entrez) 27102
Molecular Weight (g/mol) 98.6 kDa
Name Human EIF2AK1 (HRI), GST Tag
Quantity 1 mg
Regulatory Status RUO - research use only
Gene Alias EIF2AK1; eukaryotic translation initiation factor 2 alpha kinase 1; eukaryotic translation initiation factor 2-alpha kinase 1; HCR; he; heme regulated initiation factor 2 alpha kinase; heme sensitive initiation factor 2 A kinase; heme-controlled repressor; Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; heme-regulated inhibitor; heme-regulated initiation factor 2-alpha kinase; heme-regulated repressor; hemin-sensitive initiation factor 2 A kinase; hemin-sensitive initiation factor 2-alpha kinase; Hri; KIAA1369; PRO1362
Common Name HRI
KinaseFamily PEK Kinase Family
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Baculovirus
Form Liquid
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