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  5. Tocris Bioscience™ EHop 016

Tocris Bioscience™ EHop 016
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Product Code. 18738346
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5 mg
25 mg
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25mg
5mg
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18738346 25 mg 25mg
18709786 5 mg 5mg
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Product Code. 18738346 Supplier Tocris Bioscience™ Supplier No. 6248/25

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Description

Rac inhibitor

EHop 016 is a Rac inhibitor (IC50 = 1.1 μM). Exhibits some selectivity for Rac1 and Rac3 over Cdc42. Blocks the interaction of Rac with guanine nucleotide exchange factor Vav2 in breast cancer cell lines expressing high levels of Rac activity and inhibits activity of Rac downstream effector PAK1. Also inhibits mammary tumor growth and metastasis in mice.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material Rho GTPase Inhibitors
CAS 1380432-32-5
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C25H30N6O
Formula Weight Observed MW: 430.55
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