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Invitrogen™ EFHC2 Polyclonal Antibody
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Product Code. 13426137
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Quantity:
100 μL
Unit Size:
100µL
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13426137 100 μL 100µL
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Product Code. 13426137 Supplier Invitrogen™ Supplier No. PA531608

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, MCF-7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

EFHC2 (EF-hand domain-containing protein 2) is a gene located on the X chromosome at position Xp11.4. The protein encoded by EFHC2 is characterized by the presence of EF-hand motifs, which are helix-loop-helix structural domains capable of binding calcium ions. The EFHC2 protein is involved in various cellular processes, particularly those that are calcium-dependent, such as signal transduction and regulation of enzyme activities. EFHC2 has been implicated in neurological functions and conditions. For instance, it has been studied in the context of epilepsy, where variants in the gene are associated with increased susceptibility to juvenile myoclonic epilepsy. Additionally, EFHC2 is expressed in the brain and testis, suggesting roles in neurodevelopment and reproduction.
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Specifications

Antigen EFHC2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene EFHC2
Gene Accession No. Q5JST6
Gene Alias 4933407D04Rik; dJ1158H2.1; EF-hand domain (C-terminal) containing 2; EF-hand domain containing 2; EF-hand domain-containing family member C2; Efhc2; mental retardation, X-linked 74; mRib72-2; MRX74
Gene Symbols EFHC2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human EFHC2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80258
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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