Invitrogen™ EFHA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA571432

Product Code. 15829843

Description

EFHA1 Polyclonal Antibody for Western Blot

Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.

Specifications

• Antigen: EFHA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MICU2
• Gene Alias: 09C01; 1110008L20Rik; 4833427E09Rik; AU041871; Calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; EFHA1; EF-hand domain family member A1; EF-hand domain family, member A1; EF-hand domain-containing family member A1; Micu2; mitochondrial calcium uptake 2; RGD1309934; Smhs2; Smhs2 homolog
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 221154
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8IYU8
• Gene Symbols: MICU2
• Immunogen: synthetic peptide directed towards the middle region of human EFHA1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG