EFCAB4A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA561187

Product Code. 15789001

Description

Immunogen sequence: LEAVFESLDQ AHTGFLTARE FCLGLGMFVG VASAQGANPC RTPEETFESG GLDVQGTAGS LDEE Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.

EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.

Specifications

• Antigen: EFCAB4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CRACR2B
• Gene Alias: 6330520A15Rik; BC026645; Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B; calcium release activated channel regulator 2B; calcium release-activated calcium channel regulator 2B; Calcium release-activated channel regulator 2B; CRAC channel regulator 2B; CRAC regulator 2B; Cracr2a; CRACR2B; Efcab4; EFCAB4A; EF-hand calcium binding domain 4A; EF-hand calcium-binding domain-containing protein 4A; RGD1560911
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 283229
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N4Y2
• Gene Symbols: CRACR2B
• Immunogen: Recombinant protein corresponding to Human EFCAB4A
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only