Invitrogen™ EEF1G Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119900

Product Code. 17721304

Description

Positive Control: Daudi cell lysate, NIH/3T3 cell lysate, mouse cerebellum tissue, human esophagus tissue, rat pancreas tissue. Subcellular Location: cytosol, extracellular exosome, nucleus, cytoplasm, membrane.

EF-1 (elongation factor-1) is a multi-protein complex that is responsible for the delivery of aminoacyl-tRNAs to the ribosome. EF-1 gamma (elongation factor- 1 gamma), also known as EEF1G or GIG35, is a 437 amino acid subunit of the EF-1 complex. Expressed in stomach, pancreas, brain, lung, kidney, intestine, liver and spleen, EF-1 gamma contains an N-terminal Glutathione transferase domain which is thought to be involved in anchoring the complex to various cellular components. Additionally, EF-1 gamma may play a key role in the assembly of multiprotein complexes containing aminoacyl-tRNA synthetases. Increased expression of EF-1 gamma is associated with pancreatic cancer, suggesting a possible role for EF-1 gamma in the oncogenic transformation process.

Specifications

• Antigen: EEF1G
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EEF1G
• Gene Alias: 2610301D06Rik; AA407312; eEF-1B gamma; Eef1g; EF1G; EF-1-gamma; Elongation factor 1-gamma; eukaryotic translation elongation factor 1 gamma; GIG35; pancreatic tumor-related protein; PRO1608; translation elongation factor eEF-1 gamma chain
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1937, 293725, 67160
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P26641, Q68FR6, Q9D8N0
• Gene Symbols: EEF1G
• Immunogen: Synthetic peptide within human EEF1G aa 10-60/437.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG