EED226, MedChemExpress

Codice prodotto.	Quantity	unitSize
16469816	50 mg	50mg
16455997	5 mg	5mg
16433278	10 mg	10mg
16424536	100 mg	100mg

Codice prodotto. 16469816 Fornitore Medchem Express N. del fornitore HY101117

Descrizione

MedChemExpress EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model. EED226 is a potent, selective, and orally bioavailable EED inhibitor. EED226 inhibits PRC2 with an IC50 of 23.4 nM when the H3K27me0 peptide is used as a substrate in the in vitro enzymatic assays.

EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model. EED226 is a potent, selective, and orally bioavailable EED inhibitor. EED226 inhibits PRC2 with an IC50 of 23.4 nM when the H3K27me0 peptide is used as a substrate in the in vitro enzymatic assays.

Specifica

• Chemical Name or Material: EED226
• CAS: 2083627-02-3
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₁₇H₁₅N₅O₃S
• Quantity: 50 mg
• Solubility Information: DMSO : ≥ 29 mg/mL (78.51 mM)
• SMILES: O=S(C1=CC=C(C2=CN=C(NCC3=CC=CO3)N4C2=NN=C4)C=C1)(C)=O
• Molecular Weight (g/mol): 369.4
• Formula Weight: 369.4
• Percent Purity: 98.61%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only