Invitrogen™ EDG8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA523195

Product Code. 13287148

Description

The amino acid sequence used as immunogen is 84% homologous in Bovine and Porcine.

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.

Specifications

• Antigen: EDG8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: S1PR5
• Gene Alias: Edg8; Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; lpB4; Lysophospholipid receptor B4; nerve growth factor-regulated G-protein-coupled receptor 1; Nrg1; NRG-1; S1P receptor 5; S1P receptor Edg-8; S1P(5) receptor; S1P5; S1PR5; Sphingosine 1-phosphate receptor 5; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; sphingosine-1-phosphate receptor 5; sphingosine-1-phosphate receptor LPB4; SPPR-1; SPPR-2
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 53637, 60399, 610828, 94226
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q91X56, Q9H228, Q9JKM5
• Gene Symbols: S1PR5
• Immunogen: A synthetic peptide corresponding to amino acids 15-55 of human Edg8.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Monkey, Frog
• Product Type: Antibody
• Isotype: IgG