EDEM1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA556191

Product Code. 15764101

Description

Immunogen sequence: SLEKYTKVKC GYATLHHVID KSTEDRMESF FLSETCKYLY LLFDEDNPVH KSGTRYMFTT EGHIVSVDEH LRELPWKEFF SEEGGQDQGG KSVHRPKPHE LKVINSSSNC NRVPDE Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.

EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.

Specifications

• Antigen: EDEM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EDEM1
• Gene Alias: A130059K23Rik; EDEM; EDEM1; ER degradation enhancer, mannosidase alpha-like 1; ER degradation enhancing alpha-mannosidase like protein 1; ER degradation ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation-enhancing alpha-mannosidase-like protein 1; KIAA0212; mKIAA0212; RGD1563633
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9695
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92611
• Gene Symbols: EDEM1
• Immunogen: Recombinant protein corresponding to Human EDEM1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only