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Tocris Bioscience™ eCF 309, Tocris Bioscience™
Potent mTOR inhibitor
Specifications
| CAS | 2001571-40-8 |
|---|---|
| Chemical Name or Material | 3-(2-Amino-5-benzoxazolyl)-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 20mM in DMSO |
Description
Potent mTOR inhibitor (IC50 = 15 nM). Exhibits >60-fold selectivity for mTOR over PI 3-kinases and is inactive against a panel of other kinases. Inhibits growth of ER-positive MCF7 breast cancer cells in vitro (EC50 = 8.5 nM). Cell permeable.Specifications
| 2001571-40-8 | |
| 3-(2-Amino-5-benzoxazolyl)-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | |
| Bioactive Small Molecule | |
| Soluble to 20mM in DMSO |
Safety and Handling
Recommended Storage : Store at -20°C
For Research Use Only.
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