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E7449, MedChemExpress

Product Code. 16483296
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Product Code. 16483296

Brand: Medchem Express HY12418

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Description

MedChemExpress E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ∼50 and ∼50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.

E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ∼50 and ∼50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.

Specifications

Chemical Name or Material E7449
Physical Form Solid
CAS 1140964-99-3
Color Yellow
Quantity 25 mg
Purity Grade Notes Research
Molecular Formula C18H15N5O
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 6.4 mg/mL (20.17 mM; Need ultrasonic and warming)
SMILES O=C1NNC2=C3C1=CC=CC3=NC(CN4CC5=C(C=CC=C5)C4)=N2
Molecular Weight (g/mol) 317.34
Formula Weight 317.34
Percent Purity 98.0%
Grade Research
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Research purposes only

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