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E6AP Recombinant Rabbit Monoclonal Antibody (HL1660), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen MA547128

Additional Details : Weight : 0.01000kg

Product Code. 17839285

  • £362.00 / 100µL
Estimated Shipment: 20-08-2024
to see stock.

Description

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. UBE3A also plays an important role in the regulation of the circadian clock. Defects in UBE3A are a cause of Angelman syndrome (AS).
Specifications

Specifications

E6AP
Monoclonal
1 mg/mL
PBS with no preservative
Q05086
UBE3A
Recombinant protein encompassing a sequence within the center region of human UBE3A. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
Western Blot
HL1660
Unconjugated
UBE3A
4732496B02; 5830462N02Rik; A130086L21Rik; ANCR; AS; CTCL tumor antigen se37-2; E6AP; E6-AP; E6-AP ubiquitin protein ligase; E6AP ubiquitin-protein ligase; EPVE6AP; FLJ26981; HECT-type ubiquitin transferase E3A; HPVE6A; human papilloma virus E6-associated protein; human papillomavirus E6-associated protein; mKIAA4216; oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY-REN-54; UBE3A; ubiquitin conjugating enzyme E3A; ubiquitin protein ligase E3A; ubiquitin-protein ligase E3A
Rabbit
Protein A
RUO
7337
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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