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  6. Invitrogen™ E2F2 Recombinant Rabbit Monoclonal Antibody (23GB5250), Invitrogen™

Invitrogen™ E2F2 Recombinant Rabbit Monoclonal Antibody (23GB5250), Invitrogen™

Product Code. 30089383
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100 μL
Unit Size:
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20µL
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30089383 100 μL 100µL
30088084 20 μL 20µL
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Product Code. 30089383 Supplier Invitrogen™ Supplier No. MA552822

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Description

Rabbit Recombinant Monoclonal Antibody

E2F2 is a member of the E2Ffamily of transcription factors. The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressorproteins and is also a target of the transforming proteins of smallDNA tumor viruses. The E2F proteins contain several evolutionallyconserved domains found in most members of the family. Thesedomains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulatedtranscription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor proteinassociation domain which is embedded within the transactivationdomain. This protein and another 2 members, E2F1 and E2F3, have anadditional cyclin binding domain. This protein binds specificallyto retinoblastoma protein pRB in a cell-cycle dependent manner, andit exhibits overall 46% amino acid identity to E2F1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen E2F2
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB5250
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene E2F2
Gene Accession No. P56931, Q14209
Gene Alias E2F transcription factor 2; E2F2; E2F-2; LOW QUALITY PROTEIN: transcription factor E2F2; transcription factor E2F2
Gene Symbols E2F2
Host Species Rabbit
Immunogen A synthesized peptide derived from human E2F2 (313-375AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1870, 242705, 684111
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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