Invitrogen™ Dystrophin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110894

Product Code. 17188813

Description

Immunogen sequence: KQNDVHRAFK RELKTKEPVI MSTLETVRIF LTEQPLEGLE KLYQEPRELP PEERAQNVTR LLRKQAEEVN TEWEKLNLHS ADWQRKIDET LERLQELQEA TDELDLKLRQ AEVIKGSWQP VGDLLIDSLQ DHLEKVKALR GEIAPLKENV Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 98%.

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

Specifications

• Antigen: Dystrophin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DMD
• Gene Alias: apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1756
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P11532
• Gene Symbols: DMD
• Immunogen: Recombinant Protein corresonding to Human Dystrophin. Recombinant protein control fragment (Product #RP-92153).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG