Invitrogen™ Human DYRK3, GST Tag Recombinant Protein

Product Code. 15438603

Brand: Invitrogen™ PR7492A

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine/threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions. DYRK3 is a negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.

Specifications

• Accession Number: O43781
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 8444
• Molecular Weight (g/mol): 93.2 kDa
• Name: Human DYRK3, GST Tag
• Quantity: 100 μg
• Regulatory Status: RUO - research use only
• Gene Alias: BC006704; dual specificity tyrosine phosphorylation regulated kinase 3; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual specificity tyrosine-phosphorylation-regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5; dyrk3; dyrk3 {ECO:0000312; DYRK5; EMBL:AAH97474.1}; hYAK3-2; KSR; protein kinase Dyrk3; RED; REDK; regulatory erythroid kinase; RP11-343H5.2; RSU2
• Common Name: DYRK3
• KinaseFamily: DYRK Kinase Family
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Expression System: Insect cells
• Form: Liquid