Invitrogen™ DYRK2 Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA547734

Product Code. 15588222

Description

This antibody detects endogenous human, mouse and rat DYRK2 in Western blots. Reconstitute at 0.2 mg/mL in sterile PBS.

DYRK2 (also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2) belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. DYRK2 also regulates p53 to induce apoptosis in response to DNA damage.

Specifications

• Antigen: DYRK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYRK2
• Gene Alias: 1810038L18Rik; dual specificity tyrosine phosphorylation regulated kinase 2; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual specificity tyrosine-phosphorylation-regulated kinase 2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dyrk2
• Host Species: Sheep
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 314862, 69181, 8445
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q5U4C9, Q92630
• Gene Symbols: DYRK2
• Immunogen: E. coli-derived recombinant human DYRK2 Met74-Glu180.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG