Invitrogen™ DYRK1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599282

Product Code. 16623535

Description

Antibody detects endogenous levels of total DYR1B.

DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for the laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.

Specifications

• Antigen: DYRK1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYRK1B
• Gene Alias: AOMS3; dual specificity tyrosine phosphorylation regulated kinase 1B; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRK1B; DYRKB; Minibrain-related kinase; Mirk; Mirk protein kinase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13549, 9149
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9Y463, Q9Z188
• Gene Symbols: DYRK1B
• Immunogen: A synthesized peptide derived from human DYRK1B(Accession Q9Y463), corresponding to amino acid residues M336-P386.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG