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Dynein Mouse, Clone: 74.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9772-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15597666

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody 74.1 recognizes all known forms of the 74kDa intermediate chain subunit of mammalian cytoplasmic dynein. Cytoplasmic dynein is a microtubule-stimulated ATPase responsible for movement of membrane-bound organelles in a directed manner toward the minus end of microtubules, commonly found at the centrosome. Dynein is responsible for the transport of lysosomes, endosomes, phagosomes, peroxisomes, mitochondria, and vesicles from the endoplasmic reticulum destined for the Golgi. During mitosis, dynein is responsible for positioning the spindle apparatus as well as being localized to the kinetochores to facilitate chromosome movement.

The 74.1 antibody recognizes human, mouse, rat, bovine, sheep, Xenopus, porcine, and Drosophila dynein intermediate chain.
Description & Specifications

Specifications

Dynein
74.1
Unlabeled
Purified
IgG2b
RUO
Primary
Xenopus
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C.
Monoclonal