Dynein Mouse, Clone: 74.1, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9772-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg

Disclaimers: For Research Use Only.

Product Code. 15597666


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Description and Specification


Isotype IgG2b
Regulatory Status RUO
Antigen Dynein
Species Reactivity Bovine, Drosophila, Human, Mouse, Pig, Rat, Sheep, Xenopus
Monoclonal or Polyclonal Monoclonal
Applications Enzyme Linked Immunosorbent Assay
Applications Flow Cytometry (Intracellular Staining)
Applications Immunocytochemistry
Applications Immunoprecipitation
Applications Western Blotting
Storage Requirements Store at 2-8°C.
Host Species Mouse
Clone 74.1
Format Purified
Primary or Secondary Primary
Conjugate Unlabeled
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100μg
Concentration 0.5mg/mL

The monoclonal antibody 74.1 recognizes all known forms of the 74kDa intermediate chain subunit of mammalian cytoplasmic dynein. Cytoplasmic dynein is a microtubule-stimulated ATPase responsible for movement of membrane-bound organelles in a directed manner toward the minus end of microtubules, commonly found at the centrosome. Dynein is responsible for the transport of lysosomes, endosomes, phagosomes, peroxisomes, mitochondria, and vesicles from the endoplasmic reticulum destined for the Golgi. During mitosis, dynein is responsible for positioning the spindle apparatus as well as being localized to the kinetochores to facilitate chromosome movement.

The 74.1 antibody recognizes human, mouse, rat, bovine, sheep, Xenopus, porcine, and Drosophila dynein intermediate chain.