DUSP9 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16897463	Proteintech 10826-1-AP-20UL	20 μL
16887463	Proteintech 10826-1-AP-150UL	150 μL

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: DUSP9
• Applications: Immunocytochemistry, Western Blot, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q99956
• Gene ID (Entrez): 1852, 75590
• Immunogen: DUSP9 Fusion Protein Ag1259
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DUSP9

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: dual specificity phosphatase 9, DUSP9, MAP kinase phosphatase 4, MKP 4, MKP4
• Gene Symbols: DUSP9
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody