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Invitrogen™ DUSP8 Recombinant Rabbit Monoclonal Antibody (HL2338)
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Product Code. 30275407
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Quantity:
100 μL
Unit Size:
100µL
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30275407 100 μL 100µL
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Product Code. 30275407 Supplier Invitrogen™ Supplier No. MA556687

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Description

Rabbit Recombinant Monoclonal Antibody

DUSP8 Recombinant Monoclonal Antibody for Western Blot, ICC/IF

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP8
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL2338
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene DUSP8
Gene Accession No. Q13202
Gene Alias 5530400B01Rik; AI593498; C11orf81; dual specificity phosphatase 8; dual specificity protein phosphatase 8; Dual specificity protein phosphatase hVH-5; Dusp8; FLJ42476; FLJ42958; H1 phosphatase, vaccinia virus homolog; Hb5; HVH-5; HVH8; M3/6; neuronal tyrosine threonine phosphatase 1; neuronal tyrosine/threonine phosphatase 1; Nttp1; OTTHUMP00000164487; serine/threonine specific protein phosphatase; VH5
Gene Symbols DUSP8
Host Species Rabbit
Immunogen Recombinant fragment of human DUSP8.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1850, 361679
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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