Invitrogen™ DUSP5 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5122024

Product Code. 17723424

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Specifications

• Antigen: DUSP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DUSP5
• Gene Alias: candidate plasticity-related gene 21; Cpg21; dual specificity phosphatase 5; dual specificity protein phosphatase 5; dual specificity protein phosphatase 5-like; dual specificity protein phosphatase hVH3; DUSP; DUSP5; Gm337; HVH3; LOW QUALITY PROTEIN: dual specificity protein phosphatase 5; MAP-kinase phosphatase (cpg21); MAP-kinase phosphatase CPG21; serine/threonine specific protein phosphatase; VH1-like phosphatase 3; VH3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1847
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q16690
• Gene Symbols: DUSP5
• Immunogen: Recombinant Dual Specificity Phosphatase 5 (DUSP5), Met1-Arg56+Gly79-Glu135 (Accession Q16690).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG