Invitrogen™ DTYMK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5117921

Product Code. 17441583

Description

DTYMK Polyclonal Antibody for Western Blot, IHC (P), IP

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Specifications

• Antigen: DTYMK
• Classification: Polyclonal
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: P23919
• Gene Symbols: DTYMK
• Immunogen: E. coli-derived Human DTYMK fragment.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: DTYMK
• Gene Alias: AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1841
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid