Invitrogen™ DTNB Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA528883

Product Code. 13403007

Description

Recommended positive controls: mouse muscle. Predicted reactivity: Mouse (95%), Rat (96%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: DTNB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DTNB
• Gene Alias: Beta-dystrobrevin; DTNB; DTN-B; dtnb {ECO:0000250; Dystrobrevin beta; dystrobrevin, beta; mDTN-B; UniProtKB:O70585}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13528, 1838
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O60941, O70585
• Gene Symbols: DTNB
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Dystrobrevin beta. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG