Invitrogen™ DST Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5106906

Product Code. 16623345

Description

Antibody detects endogenous levels of total DST.

As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.

Specifications

• Antigen: DST
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DST
• Gene Alias: 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; 2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; BP240; BPA; Bpag; Bpag1; BPAG1-n; bullous pemphigoid antigen 1; bullous pemphigoid antigen 1, isoform 5; bullous pemphigoid antigen 1, isoforms 1/2/3/4; bullous pemphigoid antigen 1, isoforms 6/7; CATX15; CATX-15; D6S1101; DMH; DST; DT; dystonia musculorum protein; Dystonin; EBSB2; Hemidesmosomal plaque protein; HSAN6; KIAA0728; MACF2; microtubule actin cross-linking factor 2; mKIAA0728; nmf203; nmf339; trabeculin-beta
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13518, 316313, 667
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q03001, Q91ZU6
• Gene Symbols: DST
• Immunogen: A synthesized peptide derived from human DST(Accession Q03001), corresponding to amino acid residues V7423-T7473.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG