Invitrogen™ DSPG3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA561006

Product Code. 15758821

Description

Immunogen sequence: PTLESINYDS ETYDATLEDL DNLYNYENIP VDKVEIEIAT VMPSGNRELL TPPPQPEKAQ EEEEE Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 55%.

The DSPG3 gene is not well-characterized and does not appear in standard genomic databases as a distinct gene or protein coding entity. It is possible that DSPG3 refers to a specific type of dermatan sulfate proteoglycan, given the acronym DSPG, which typically relates to proteoglycans involved in extracellular matrix structure and modulation. Proteoglycans like dermatan sulfate proteoglycans are pivotal in maintaining tissue resilience and regulating cell signaling pathways by interacting with growth factors and cytokines. They contribute to developmental processes and tissue repair mechanisms, playing roles in cellular adhesion, proliferation, and migration. In the context of skeletal and connective tissues, DSPGs influence matrix assembly and modulate biomechanical properties, impacting processes such as angiogenesis and fibrosis. Proteoglycans are known for their importance in disease states, including cancer and fibrosis, where altered expression or structure can affect cellular interactions and disease progression. Further research is needed to understand the specifics of DSPG3's functions and its implications in health and disease.

Specifications

• Antigen: DSPG3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPYC
• Gene Alias: Dermatan sulfate proteoglycan 3; dermatan sulphate proteoglycan 3; Dspg3; DSPG3proteoglycan-lb; Epiphycan; epiphycan proteoglycan; EPYC; Pglb; PG-Lb; Proteoglycan-Lb; SLRR3B; Small chondroitin/dermatan sulfate proteoglycan
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1833
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q99645
• Gene Symbols: EPYC
• Immunogen: Recombinant protein corresponding to Human DSPG3. Recombinant protein control fragment (Product #RP-97642).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG