Invitrogen™ DSPG3 Monoclonal Antibody (340908)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA524074

Product Code. 15573762

Description

In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human DSPG3 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

The DSPG3 gene is not well-characterized and does not appear in standard genomic databases as a distinct gene or protein coding entity. It is possible that DSPG3 refers to a specific type of dermatan sulfate proteoglycan, given the acronym DSPG, which typically relates to proteoglycans involved in extracellular matrix structure and modulation. Proteoglycans like dermatan sulfate proteoglycans are pivotal in maintaining tissue resilience and regulating cell signaling pathways by interacting with growth factors and cytokines. They contribute to developmental processes and tissue repair mechanisms, playing roles in cellular adhesion, proliferation, and migration. In the context of skeletal and connective tissues, DSPGs influence matrix assembly and modulate biomechanical properties, impacting processes such as angiogenesis and fibrosis. Proteoglycans are known for their importance in disease states, including cancer and fibrosis, where altered expression or structure can affect cellular interactions and disease progression. Further research is needed to understand the specifics of DSPG3's functions and its implications in health and disease.

Specifications

• Antigen: DSPG3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P70186
• Gene Symbols: EPYC
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse DSPG3 Ala20-Ile322.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 340908
• Conjugate: Unconjugated
• Gene: EPYC
• Gene Alias: Dermatan sulfate proteoglycan 3; dermatan sulphate proteoglycan 3; Dspg3; DSPG3proteoglycan-lb; Epiphycan; epiphycan proteoglycan; EPYC; Pglb; PG-Lb; Proteoglycan-Lb; SLRR3B; Small chondroitin/dermatan sulfate proteoglycan
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 13516
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized