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Invitrogen™ DRD3 Recombinant Rabbit Monoclonal Antibody (23GB5840), Invitrogen™
Description
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Specifications
Specifications
| Antigen | DRD3 |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB5840 |
| Concentration | 0.333 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | DRD3 |
| Gene Accession No. | P19020, P30728, P35462 |
| Gene Alias | D(3) dopamine receptor; D3 receptor; D3DR; D3nf; D3R; Dopamine 3 receptor; Dopamine D3 receptor; dopamine receptor 3; dopamine receptor D3; dopaminergic receptor D3; Drd3; essential tremor 1; ETM1; FET1 |
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