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DR3, PE, clone: JD3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-6603-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15597066

  • £174.50 / 100 tests


Estimated Shipment date
from Supplier 23-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The JD3 monoclonal antibody reacts with human DR3, also known as Apo-3, WSL-1, TRAMP, LARD, DDR3, and TR3. DR3, a novel death receptor is expressed at low level by monocytes and granulocytes. Interaction of DR3 with its ligand activates NF-kappa B pathway and induces apoptosis. Initially, DR3 was thought to be a receptor for TWEAK, but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3. JD3 has been reported for use in flow cytometric analysis.Applications Reported: The JD3 antibody has been reported for use in flow cytometric analysis.Applications Tested: This JD3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells and human DR3-transfected cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

DR3
JD3
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TRAMP, Apo-3, TRAIL Receptor family, Tyrosine-rich acidic matrix protein
IgG1
RUO
Primary
Human
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