DR3 Mouse anti-Human, PE, Clone: JD3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-6603-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15597066

Quantity Price
1 £ 170.59 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Host Species Murine
Quantity 100 Tests
Regulatory Status RUO
Antigen DR3
Isotype IgG1
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Species Reactivity Human
Clone JD3
Gene Alias TRAMP, Apo-3, TRAIL Receptor family, Tyrosine-rich acidic matrix protein
Concentration 5μL (0.125μg)/test
Conjugate PE
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary

The JD3 monoclonal antibody reacts with human DR3, also known as Apo-3, WSL-1, TRAMP, LARD, DDR3, and TR3. DR3, a novel death receptor is expressed at low level by monocytes and granulocytes. Interaction of DR3 with its ligand activates NF-kappa B pathway and induces apoptosis. Initially, DR3 was thought to be a receptor for TWEAK, but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3. JD3 has been reported for use in flow cytometric analysis.