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DR3, PE, clone: JD3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-6603-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15597066

  • £174.50 / 100 tests


Estimated Shipment date
from Supplier 05-06-2018
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Description

Description

Description: The JD3 monoclonal antibody reacts with human DR3, also known as Apo-3, WSL-1, TRAMP, LARD, DDR3, and TR3. DR3, a novel death receptor is expressed at low level by monocytes and granulocytes. Interaction of DR3 with its ligand activates NF-kappa B pathway and induces apoptosis. Initially, DR3 was thought to be a receptor for TWEAK, but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3. JD3 has been reported for use in flow cytometric analysis.Applications Reported: The JD3 antibody has been reported for use in flow cytometric analysis.Applications Tested: This JD3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells and human DR3-transfected cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

DR3
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q93038
APO3, apoptosis inducing receptor, apoptosis-inducing receptor AIR, apoptosis-mediating receptor DR3, apoptosis-mediating receptor TRAMP, DDR3, death domain receptor 3 soluble form, death receptor beta, DR3, lymphocyte-associated receptor of death, protein WSL-1, TNFRSF12, tumor necrosis factor receptor superfamily member 25, tumor necrosis factor receptor superfamily, member 12, tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein), tumor necrosis factor receptor superfamily, member 25, WSL, WSL1
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
JD3
PE
TNFRSF25
Conjugated
TNFRSF25
IgG1, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
8718
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