Invitrogen™ DPPA4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA580562

Product Code. 16347674

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human DPPA4.

The DPPA4 gene encodes developmental pluripotency associated 4, a protein that plays a crucial role in maintaining stem cell pluripotency and facilitating early embryonic development. DPPA4 is primarily expressed in pluripotent stem cells, such as embryonic stem cells, where it contributes to the regulation of gene expression and chromatin structure necessary for pluripotency and differentiation. This protein is also involved in the establishment of epigenetic marks that influence developmental pathways, ensuring the proper formation of tissue types during embryogenesis. DPPA4 functions in stem cell renewal and differentiation, impacting cellular processes that are fundamental to early development. Beyond its roles in normal physiology, DPPA4 has been studied in the context of oncology, where its expression is often upregulated in certain cancers, indicating its potential as a biomarker for tumorigenic stem cell-like properties. Research continues to explore DPPA4's mechanisms and interactions to understand its contributions to development and its implications in disease states, particularly in cancer biology and regenerative medicine.

Specifications

• Antigen: DPPA4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DPPA4
• Gene Alias: 2410091M23Rik; C76608; developmental pluripotency associated 4; developmental pluripotency-associated protein 4; Dppa4; ECAT15-1; Embryonic stem cell-associated transcript 15-1 protein; LOC685378; similar to developmental pluripotency associated 4 isoform 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55211
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q7L190
• Gene Symbols: DPPA4
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Human DPPA4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG