Doxycycline hyclate, Thermo Scientific™

Doxycycline hyclate, Doryx, CAS # 24390-14-5, is the hyclate salt form of the broad-spectrum antibiotic known as doxycycline.

Brand:  Thermo Scientific Alfa Aesar J60579.22

Product Code. 15473329

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General description
• Doxycycline hyclate is a broad-spectrum bacteriostatic antibiotic of the tetracycline class
• Doxycycline inhibits bacterial growth by preventing polypeptide formation via inhibition of at least one ribosomal subunit
• Known to reversibly bind the 30S ribosomal subunit and inhibit formation of the aminoacyl-tRNA/mRNA-ribosome complex
• Inhibits matrix metalloproteinases in many microorganisms
Applications
• Effective against the bacteria that cause Lyme disease, chlamydia, rickettsia and mycoplasma; suitable for antibiotic resistance testing and study of cellular mechanisms
• Intended for laboratory use only

Chemical Identifiers

• CAS: 24390-14-5
• Molecular Weight (g/mol): 609.066
• InChI Key: ISZOFWGVNMFENH-YDLUHMIOSA-N
• PubChem CID: 131676157
• SMILES: CCO.CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.O.Cl

• Molecular Formula: C26H41ClN2O12
• MDL Number: MFCD07357237
• Synonym: Hydramycin; Doxycycline Hydrochloride Hemiethanolate Hemihydrate
• IUPAC Name: (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;dihydrate;hydrochloride

Specifications

• CAS: 24390-14-5
• Quantity: 100g
• MDL Number: MFCD07357237
• Synonym: Hydramycin; Doxycycline Hydrochloride Hemiethanolate Hemihydrate
• InChI Key: ISZOFWGVNMFENH-YDLUHMIOSA-N
• IUPAC Name: (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;dihydrate;hydrochloride
• PubChem CID: 131676157
• Chemical Name or Material: Doxycycline hyclate

• Color: Yellow
• Molecular Formula: C26H41ClN2O12
• Merck Index: 14,3440
• Solubility Information: Soluble in water to 50mg/ml; May require warming;Soluble in water,methanol; Sparingly soluble in ethanol; Insoluble in chloroform and ether.
• SMILES: CCO.CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.O.Cl
• Molecular Weight (g/mol): 609.066
• Formula Weight: 512.94 (503.94 Anhydrous)