Doxycycline hyclate

Product Code.	Quantity	Unit Size
15463329	25 g	25g
15473329	100 g	100g

Product Code. 15463329 Supplier Thermo Scientific Alfa Aesar Supplier No. J60579.14

Description

Doxycycline hyclate, Doryx, CAS # 24390-14-5, is the hyclate salt form of the broad-spectrum antibiotic known as doxycycline. | CAS: 24390-14-5 | C26H41ClN2O12 | 609.066 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

General description
• Doxycycline hyclate is a broad-spectrum bacteriostatic antibiotic of the tetracycline class
• Doxycycline inhibits bacterial growth by preventing polypeptide formation via inhibition of at least one ribosomal subunit
• Known to reversibly bind the 30S ribosomal subunit and inhibit formation of the aminoacyl-tRNA/mRNA-ribosome complex
• Inhibits matrix metalloproteinases in many microorganisms
Applications
• Effective against the bacteria that cause Lyme disease, chlamydia, rickettsia and mycoplasma; suitable for antibiotic resistance testing and study of cellular mechanisms
• Intended for laboratory use only

Specifications

Chemical Identifiers

• CAS: 24390-14-5
• Molecular Formula: C26H41ClN2O12
• Molecular Weight (g/mol): 609.066
• MDL Number: MFCD07357237
• InChI Key: ISZOFWGVNMFENH-YDLUHMIOSA-N
• PubChem CID: 131676157
• IUPAC Name: (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;dihydrate;hydrochloride
• SMILES: CCO.CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.O.Cl

• Type: Doxycycline Hyclate
• Physical Form: Powder
• Color: Yellow
• Quantity: 25 g
• Merck Index: 14,3440
• Synonym: Hydramycin; Doxycycline hydrochloride hemiethanolate hemihydrate
• Solubility Information: Soluble in water to 50mg/ml; May require warming;Soluble in water,methanol; Sparingly soluble in ethanol; Insoluble in chloroform and ether.
• Formula Weight: 512.94 (503.94 Anhydrous)
• Chemical Name or Material: Doxycycline hyclate

Safety and Handling

Product Identifier

• Doxycycline hyclate

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H361fd-Suspected of damaging fertility. Suspected of damaging the unborn child.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contain: Doxycycline hyclate

SDS

RUO – Research Use Only