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  6. Doxorubicin hydrochloride, MedChemExpress

Doxorubicin hydrochloride, MedChemExpress

Product Code. 16406646
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Product Code. 16406646

Brand: Medchem Express HY15142

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Description

MedChemExpress Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent.

Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.

Specifications

Chemical Name or Material Doxorubicin hydrochloride
Physical Form Solid
CAS 25316-40-9
Color Reddish Brown
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C27H30ClNO11
For Use With (Application) Cancer-Kinase/protease
Synonym Hydroxydaunorubicin hydrochloride
Solubility Information DMSO : 35.71 mg/mL (61.57 mM; ultrasonic and warming and heat to 60°C) ∣H2O : 20 mg/mL (34.48 mM; Need ultrasonic)
SMILES COC1=C2C(C(C(C(O)=C(C[C@](C(CO)=O)(O)C[C@@H]3O[C@@]4([H])C[C@H](N)[C@H](O)[C@H](C)O4)C3=C5O)=C5C2=O)=O)=CC=C1.[H]Cl
Molecular Weight (g/mol) 579.98
Formula Weight 579.98
Percent Purity 95.0%
Grade Research
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Research purposes only

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