Invitrogen™ DOT5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5144420

Product Code. 17920553

Description

DOT5 Polyclonal Antibody for Western Blot, ELISA

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Has a role in telomere silencing, which is the repression of chromatin structure which leads to a stop in the transcription of nearby genes. Also has a role in the regulation of telomere length. Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth. Preferentially reduces alkyl-hydroperoxides rather than hydrogen peroxide. Acts as an antioxidant necessary for stationary phase survival.

Specifications

• Antigen: DOT5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DOT5
• Gene Alias: Peroxiredoxin DOT5 DOT5 YIL010W
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 854805
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3.9 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene Accession No.: P40553
• Gene Symbols: DOT5
• Immunogen: Recombinant Saccharomyces cerevisiae (strain ATCC 204508/S288c) (Baker's yeast) DOT5 protein (37-118aa).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Yeast
• Product Type: Antibody
• Isotype: IgG