Invitrogen™ DOCK8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5140262

Product Code. 17834780

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: INRYSSAEIR KQFTLPPNLG QYHRQSISTS GFPSLQLPQF YDPVEPVDFE GLLMTHLNSL DVQLAQELGD FTDDDLDVVF Highest antigen sequence indentity to the following orthologs: Mouse - 88%, Rat - 86%.

The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors. DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.

Specifications

• Antigen: DOCK8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dock8
• Gene Alias: 1200017A24Rik; 5830472H07Rik; A130095G14Rik; AI461977; dedicator of cytokinesis 8; dedicator of cytokinesis protein 8; Dock8; epididymis luminal protein 205; HEL-205; MRD2; ZIR8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81704
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NF50
• Gene Symbols: Dock8
• Immunogen: Recombinant protein corresponding to Human DOCK8. Recombinant protein control fragment (Product #RP-109342).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG