Invitrogen™ DOCK5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA566045

Product Code. 15918774

Description

Immunogen sequence: VELSVLFCKFI QSIPDNQLVR QKLNCMTKIV ESTLFRQSEC REVLLPLLTD QLSGQLDDNS NKPDHEASSQ LL Highest antigen sequence identity to the following orthologs - mouse 92%, rat 92%.

Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).

Specifications

• Antigen: DOCK5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DOCK5
• Gene Alias: dedicator of cytokinesis 5; dedicator of cytokinesis protein 5; DOCK5; FLJ21034
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80005
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H7D0
• Gene Symbols: DOCK5
• Immunogen: Recombinant Human DOCK5. Recombinant protein control fragment (Product #RP-106733).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG