Invitrogen™ DNase II Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115136

Product Code. 17217903

Description

Antibody detects endogenous levels of total DNase II.

DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

Specifications

• Antigen: DNase II
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNASE2
• Gene Alias: acid DNase; deoxyribonuclease; Deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; DNASE2; Dnase2a; DNL; Dnl2; lysosomal DNase II; R31240_2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171575, 1777
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O00115, Q9QZK8
• Gene Symbols: DNASE2
• Immunogen: A synthesized peptide derived from human DNASE2(Accession O00115), corresponding to amino acid residues E209-T259.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG