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Invitrogen™ DLK1 Monoclonal Antibody (3A10)
Description
MA5-15915 targets DLK1 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15915 immunogen is purified recombinant fragment of human DLK1 expressed in E. Coli. . MA5-15915 detects DLK1 which has a predicted molecular weight of approximately 41kDa.
The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
Specifications
Specifications
| Antigen | DLK1 |
| Applications | ELISA, Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 3A10 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | Ascites with 0.03% sodium azide |
| Gene | DLK1 |
| Gene Accession No. | P80370, Q09163 |
| Gene Alias | Adipocyte differentiation inhibitor protein; AW742678; delta like non-canonical Notch ligand 1; Delta1; delta-like 1 homolog; delta-like 1 homolog (Drosophila); DLK; Dlk1; DLK-1; DlkI; FA1; Fetal antigen 1; Ly107; Peg9; pG2; Preadipocyte factor 1; preadipocyte factor-1; PREF; Pref1; pref-1; Protein delta homolog 1; SCP1; Scp-1; secredeltin; stromal cell derived protein 1; ZOG |
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