DL-Dithiothreitol, MP Biomedicals™

Product Code.	Quantity	unitSize
11445832	5 g	5g

Product Code. 11445832 Supplier MP Biomedicals Supplier No. 04856126

Descripción

DL-Dithiothreitol, Electrophoresis grade, ≥99.5%, White Powder

• Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes.
• Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE.
• DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel.
• DTT is less pungent and is less toxic than 2-mercaptoethanol.
• DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH).
• In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution.

Especificaciones

Identificadores de productos químicos

• CAS: 12-3-3483
• Molecular Formula: C4H10O2S2
• Molecular Weight (g/mol): 154.24
• MDL Number: MFCD00004877
• InChI Key: VHJLVAABSRFDPM-IMJSIDKUSA-N
• Synonym: 1,4-Dithiothreitol, DTT, 1,4-Dithio-DL-threitol, Cleland Reagent

• Melting Point: 40°C to 50°C
• Color: White
• pH: 4.0 to 6.0 (0.1 M in H2O, 25°C)
• Flash Point: 113°C / 235.4°F (lit.)
• Quantity: 5 g
• UN Number: UN3335
• Beilstein: 1719757
• Solubility Information: Soluble in water (50mg/mL - clear and colorless solution); soluble in ethanol, acetone, ethylate, chloroform and ether.
• Grade: ≥99.5%
• Physical Form: Powder

Seguridad y manipulación

Nombre del producto

• DL-Dithiothreitol, electrophoresis grade

Palabra de advertencia

• Warning

Clasificación

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Indicaciones de peligro

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Consejos de prudencia

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P321-Specific treatment (see on this label).
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Otros peligros

• MIXTURE LIST-Contain: DL-Dithiothreitol