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DL-Dithiothreitol, MP Biomedicals™

Product Code. 11445832 Shop All MP Biomedicals Products
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Quantity:
5 g
Unit Size:
5g
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Product Code. 11445832

Brand: MP Biomedicals 04856126

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120.03 GBP valid until 2025-12-14
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Description

DL-Dithiothreitol, Electrophoresis grade, ≥99.5%, White Powder

  • Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes.
  • Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE.
  • DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel.
  • DTT is less pungent and is less toxic than 2-mercaptoethanol.
  • DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH).
  • In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 12-3-3483
Molecular Formula C4H10O2S2
Molecular Weight (g/mol) 154.24
MDL Number MFCD00004877
InChI Key VHJLVAABSRFDPM-IMJSIDKUSA-N
Synonym 1,4-Dithiothreitol, DTT, 1,4-Dithio-DL-threitol, Cleland Reagent

Specifications

Melting Point 40°C to 50°C
Color White
pH 4.0 to 6.0 (0.1 M in H2O, 25°C)
Flash Point 113°C / 235.4°F (lit.)
Quantity 5 g
UN Number UN3335
Beilstein 1719757
Solubility Information Soluble in water (50mg/mL - clear and colorless solution); soluble in ethanol, acetone, ethylate, chloroform and ether.
Grade ≥99.5%
Physical Form Powder

Safety and Handling

compliance-icons
Product Identifier
  • DL-Dithiothreitol, electrophoresis grade
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P264-Wash thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : DL-Dithiothreitol
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