Diphenyl phosphorochloridate, 97%

Product Code.	Quantity	unitSize
11400034	50 g	50g
11410034	250 g	250g
11490024	1000 g	1000g

Product Code. 11400034

Brand: Thermo Scientific Alfa Aesar A13546.18

Description

CAS: 2524-64-3 | C12H10ClO3P | 268.633 g/mol

Diphenyl phosphorochloridate is used to prepare cyclohexyl-amidophosphoric acid diphenyl ester by reacting with cyclohexylamine. It is also used in the synthesis of alfa-substituted beta-lactams, anhydrides, esters and thioesters. It is also employed in the conversion of aldoximes to nitriles. Further, it is used in the preparation and reaction of enol phosphates, guanosine-adenosine-5',5'-triphosphate, guanosine-cytidine-5',5'-triphosphate, guanosine-uridine-5',5'-triphosphate, diguanosine-5',5'-diphosphate and diguanosine-5',5'-triphosphate. In addition to this, it serves as a phosphorylating agent for the preparation of 2-deoxy-D-galactose-3 and -6 phosphoric acids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diphenyl phosphorochloridate is used to prepare cyclohexyl-amidophosphoric acid diphenyl ester by reacting with cyclohexylamine. It is also used in the synthesis of alfa-substituted beta-lactams, anhydrides, esters and thioesters. It is also employed in the conversion of aldoximes to nitriles. Further, it is used in the preparation and reaction of enol phosphates, guanosine-adenosine-5′,5′-triphosphate, guanosine-cytidine-5′,5′-triphosphate, guanosine-uridine-5′,5′-triphosphate, diguanosine-5′,5′-diphosphate and diguanosine-5′,5′-triphosphate. In addition to this, it serves as a phosphorylating agent for the preparation of 2-deoxy-D-galactose-3 and -6 phosphoric acids.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Incompatible with strong bases and strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 2524-64-3
• Molecular Formula: C12H10ClO3P
• Molecular Weight (g/mol): 268.633
• MDL Number: MFCD00003030
• InChI Key: BHIIGRBMZRSDRI-UHFFFAOYSA-N
• Synonym: diphenyl chlorophosphate, diphenyl phosphorochloridate, diphenylchlorophosphate, phosphorochloridic acid, diphenyl ester, chlorodiphenyl phosphate, o,o-diphenyl chlorophosphate, chlorodiphenoxyphosphine oxide, diphenoxychlorophosphine oxide, diphenyl chlorophosphonate, diphenylphosphoric acid monochloride
• PubChem CID: 75654
• IUPAC Name: [chloro(phenoxy)phosphoryl]oxybenzene
• SMILES: C1=CC=C(C=C1)OP(=O)(OC2=CC=CC=C2)Cl

• Density: 1.296
• Boiling Point: 145°C to 147°C (1 mmHg)
• Flash Point: 113°C (235°F)
• Refractive Index: 1.55
• Quantity: 50 g
• UN Number: UN3265
• Beilstein: 654130
• Sensitivity: Moisture sensitive
• Solubility Information: Immiscible with water.
• Formula Weight: 268.64
• Percent Purity: 97%
• Chemical Name or Material: Diphenyl phosphorochloridate

Safety and Handling

SDS

RUO – Research Use Only