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Diethylaminoethyl dextran

Product Code. 15455949
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25 g
100 g
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25g
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Product Code. 15455949 Supplier Thermo Scientific Alfa Aesar Supplier No. J63781.14
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Description

CAS: 9015-73-0

DEAE-Dextran is used in the development of sustained release protein delivery and nucleic acid transfection systems. It has been speculated that DEAE-Dextran may cause a stimulation of the helper T-cell function in antibody synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
DEAE-Dextran is used in the development of sustained release protein delivery and nucleic acid transfection systems. The use of DEAE-Dextran as an efficient adjuvant in vaccine production is well established. For instance, DEAE-Dextran has been used for immunization of guinea pigs and swine with inactivated foot-and-mouth disease and rhesus monkeys with inactivated Venezulean equine encephalomyelitis virus, IVEE. The mechanism of action of DEAE-Dextran is not clear. The effect on the humoral response of rhesus monkeys to IVEE vaccine results in a typical IgM-IgG response. It has been speculated that DEAE-Dextran may cause a stimulation of the helper T-cell function in antibody synthesis.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 9015-73-0
MDL Number MFCD00081561
Synonym DEAE-Dextran
IUPAC Name Diethylaminoethyl dextran

Specifications

Color White
Quantity 25 g
Merck Index 14,2936
Solubility Information Soluble in water.
Physical Form Powder
Chemical Name or Material Diethylaminoethyl dextran

RUO – Research Use Only

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