Alfa Aesar™ Diethyl cyanomethylphosphonate, 98+%


Overview
Brand: Alfa Aesar™

Manufacturer Part Number: A10218.14

UNSPSC: 12352128

Code: NEW

Additional Details:
Additional Details: CAS Number: 2537-48-6 Weight: 0.01000kg


Quantity 25g

Product Code. 11449552

Quantity Price
1 £ 35.19 / 25g
Estimated Shipment date
from Supplier 12-04-2017
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Description and Specification

Chemical Identifiers

Chemical Name or Material Diethyl cyanomethylphosphonate
CAS 2537-48-6
Molecular Formula C6H12NO3P
Formula Weight 177.14
MDL Number MFCD00001893
UN Number UN3278
Beilstein 1772981
Synonym Cyanomethylphosphonic acid diethyl ester; Diethyl phosphonoacetonitrile

Specification

Formula Weight 177.14
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Molecular Formula C6H12NO3P
Chemical Name or Material Diethyl cyanomethylphosphonate
Quantity 25g
DOT Information Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: ORGANOPHOSPHORUS COMPOUND, LIQUID, TOXIC, N.O.S.
CAS 2537-48-6
Health Hazard 2 GHS H Statement
H331-H302-H312-H315-H319
Toxic if inhaled.
Harmful if swallowed.
Harmful in contact with skin.
Causes skin irritation.
Causes serious eye irritation.
Synonym Cyanomethylphosphonic acid diethyl ester; Diethyl phosphonoacetonitrile
Flash Point >110°C (230°F)
Boiling Point 132° to 135°C (1.2mmHg)
Beilstein 1772981
Assay ≥98%
UN Number UN3278
Health Hazard 1 Danger
MDL Number MFCD00001893

Applications
Diethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.

Solubility
Miscible with water, chloroform, terahydrofuran, ethyl acetate and methylene chloride.

Notes
Incompatible with acids, bases, oxidizing agents and reducing agents.

Documentation

Technical documents

Safety and Handling

Danger

GHS H Statement
H331-H302-H312-H315-H319
Toxic if inhaled.
Harmful if swallowed.
Harmful in contact with skin.
Causes skin irritation.
Causes serious eye irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.