Invitrogen™ DGCR8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA540122

Product Code. 15546811

Description

Recommended positive controls: 293T, A431, HeLa, and HepG2 cells. Predicted reactivity: Mouse (82%), Rat (80%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: DGCR8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DGCR8
• Gene Alias: C22orf12; D16H22S1742E; D16H22S788E; D16Wis2; DGCR8; DGCR8 microprocessor complex subunit; DGCR8, microprocessor complex subunit; DGCRK6; DiGeorge syndrome critical region 8; diGeorge syndrome critical region 8 homolog; DiGeorge syndrome critical region gene 8; Gy1; LP4941; Microprocessor complex subunit DGCR8; mir-1306; N41; pasha; sb:eu827; sb:eu832; si:ch211-106a19.4; Vo59c07; wu:fc23f08; wu:fc38f06
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54487
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.15 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q8WYQ5
• Gene Symbols: DGCR8
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human DGCR8. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Amphibian, Human
• Product Type: Antibody
• Isotype: IgG