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Deucravacitinib, MedChemExpress

Product Code. 16471127
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Product Code. 16471127 Supplier Medchem Express Supplier No. HY117287

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Description

MedChemExpress Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways.

Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways.

Specifications

Chemical Name or Material Deucravacitinib
CAS 1609392-27-9
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C20H19D3N8O3
Quantity 50 mg
Synonym BMS-986165
Solubility Information DMSO : 37.5 mg/mL (88.14 mM; Need ultrasonic)
SMILES O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H]
Molecular Weight (g/mol) 425.46
Formula Weight 425.46
Percent Purity 98.44%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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