Invitrogen™ Desmoglein 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA569369

Product Code. 15817783

Description

This target displays homology in the following species: Cow: 93%; Dog: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 85%; Rat: 100%. Synthetic peptide located within the following region: TDADEVGSDN WLANFTFASG NEGGYFHIET DTQTNEGIVT LVKEVDYEEM.

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Specifications

• Antigen: Desmoglein 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DSG2
• Gene Alias: AA408168; ARVC10; ARVD10; Cadherin family member 5; CDHF5; CMD1BB; D18Ertd293e; desmoglein 2; desmoglein-2; DSG2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13511
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O55111
• Gene Symbols: DSG2
• Immunogen: synthetic peptide directed towards the middle region of mouse Desmoglein 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG